GMM-based molecular serum profiling framework
Fragment książki (Materiały konferencyjne)
MNiSW
15
WOS
| Status: | |
| Autorzy: | Plechawska-Wójcik Małgorzata |
| Wersja dokumentu: | Drukowana | Elektroniczna |
| Arkusze wydawnicze: | 0.8 |
| Język: | angielski |
| Strony: | 57 - 70 |
| Web of Science® Times Cited: | 0 |
| Scopus® Cytowania: | 1 |
| Bazy: | Web of Science | Scopus | Web of Science Core Collection | Scopus |
| Efekt badań statutowych | NIE |
| Materiał konferencyjny: | TAK |
| Nazwa konferencji: | 21st International Conference, ICIST 2015 |
| Termin konferencji: | 15 października 2015 do 16 października 2015 |
| Miasto konferencji: | Druskininkai |
| Państwo konferencji: | LITWA |
| Publikacja OA: | NIE |
| Abstrakty: | angielski |
| The paper presents GMM-based molecular serum profiling framework dedicated to complete analyzing of Maldi-ToF mass spectrometry data. The presented Matlab-based framework is a comprehensive, self-adapting solution dedicated to different kind of spectra datasets. The process of mass spectrometry data analysis consists of several procedures, like data preparation, data pre-processing including baseline correction, detection of outliers and noise removal. The mean spectrum is calculated, modeled with GMM and decomposed using the Expectation-Maximization algorithm. In this process localization of the mean spectrum peaks is done with the dedicated adaptive procedure. Results of the mean spectrum decomposition in the subsequent step are applied into each single spectrum in the dataset in the form of Gaussian mask. The result is a data set ready for further statistical analysis |
