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Aggrandized fluctuations in the series of reaction times (RTs) are a very sensitive marker of neurocognitive disorders present in neuropsychiatric populations, pathological ageing and in patients with acquired brain injury. Even though it was documented that processing inconsistency founds a background of higher-order cognitive functions disturbances, there is a vast heterogeneity regarding types of task used to compute RT-related variability, which impedes determining the relationship between elementary and more complex cognitive processes. Considering the above, our goal was to develop a relatively new assessment method based on a simple reaction time paradigm, conducive to eliciting a controlled range of intra-individual variability. It was hypothesized that performance variability might be induced by manipulation of response-stimulus interval’s length and regularity. In order to verify this hypothesis, a group of 107 healthy students was tested using a series of digitalized tasks and their results were analyzed using parametric and ex-Gaussian statistics of RTs distributional markers. In general, these analyses proved that intra-individual variability might be evoked by a given type of response-stimulus interval manipulation even when it is applied to the simple reaction time task. Collected outcomes were discussed with reference to neuroscientific concepts of attentional resources and functional neural networks.