Niacin Skin Flush Backs—From the Roots of the Test to Nowadays Hope
Artykuł przeglądowy (review)
MNiSW
140
Lista 2023
Status: | |
Autorzy: | Sitarz Ryszard, Juchnowicz Dariusz, Karakuła Kaja, Forma Alicja, Baj Jacek, Róg Joanna, Karpiński Robert, Machrowska Anna, Karakuła-Juchnowicz Hanna |
Dyscypliny: | |
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Rok wydania: | 2023 |
Wersja dokumentu: | Elektroniczna |
Język: | angielski |
Numer czasopisma: | 5 |
Wolumen/Tom: | 12 |
Numer artykułu: | 1879 |
Strony: | 1 - 16 |
Impact Factor: | 3,0 |
Web of Science® Times Cited: | 2 |
Scopus® Cytowania: | 4 |
Bazy: | Web of Science | Scopus |
Efekt badań statutowych | NIE |
Finansowanie: | This research was funded by Medical University of Lublin grant number PBsd101 |
Materiał konferencyjny: | NIE |
Publikacja OA: | TAK |
Licencja: | |
Sposób udostępnienia: | Witryna wydawcy |
Wersja tekstu: | Ostateczna wersja opublikowana |
Czas opublikowania: | W momencie opublikowania |
Data opublikowania w OA: | 27 lutego 2023 |
Abstrakty: | angielski |
The niacin skin flush test (NSFT) is a simple method used to assess the content of fatty acids in cell membranes and is a possible indicator of factors hidden behind various outcomes in patients. The purpose of this paper is to determine the potential usefulness of NSFT in mental disorder diagnostics along with the determination of factors that may affect its results. The authors reviewed articles from 1977 onwards, focusing on the history, variety of methodologies, influencing factors, and proposed mechanisms underlying its performance. Research indicated that NSFT could be applicable in early intervention, staging in psychiatry, and the search for new therapeutic methods and drugs based on the mechanisms of NSFT action. The NSFT can contribute to defining an individualized diet for patients and prevent the development of damaging disease effects at an early stage. There is promising evidence for supplementation with polyunsaturated fatty acids, which have a beneficial influence on the metabolic profile and are effective even in the subclinical phase of the disease. NSFT can contribute to the new classification of diseases and a better understanding of certain mental disorders’ pathophysiology. However, there is a need to establish a validated method for assessing the NSFT results. |