Analysis of the distribution of magnetic fluid inside tumors by a giant magnetoresistance probe
Artykuł w czasopiśmie
MNiSW
40
Lista A
| Status: | |
| Autorzy: | Gooneratne Chinthaka P., Kurnicki Adam, Yamada Sotoshi , Mukhopadhyay Subhas C. , Kosel Jürgen |
| Rok wydania: | 2013 |
| Wersja dokumentu: | Elektroniczna |
| Język: | angielski |
| Numer czasopisma: | 11 |
| Wolumen/Tom: | 8 |
| Strony: | 1 - 14 |
| Impact Factor: | 3,534 |
| Web of Science® Times Cited: | 15 |
| Scopus® Cytowania: | 8 |
| Bazy: | Web of Science | Scopus | SCOPUS |
| Efekt badań statutowych | NIE |
| Materiał konferencyjny: | NIE |
| Publikacja OA: | TAK |
| Licencja: | |
| Sposób udostępnienia: | Otwarte czasopismo |
| Wersja tekstu: | Ostateczna wersja opublikowana |
| Czas opublikowania: | W momencie opublikowania |
| Abstrakty: | angielski |
| Magnetic fluid hyperthermia (MFH) therapy uses the magnetic component of electromagnetic fields in the radiofrequency spectrum to couple energy to magnetic nanoparticles inside tumors. In MFH therapy, magnetic fluid is injected into tumors and an alternating current (AC) magnetic flux is applied to heat the magnetic fluid- filled tumor. If the temperature can be maintained at the therapeutic threshold of 42°C for 30 minutes or more, the tumor cells can be destroyed. Analyzing the distribution of the magnetic fluid injected into tumors prior to the heating step in MFH therapy is an essential criterion for homogenous heating of tumors, since a decision can then be taken on the strength and localization of the applied external AC magnetic flux density needed to destroy the tumor without affecting healthy cells. This paper proposes a methodology for analyzing the distribution of magnetic fluid in a tumor by a specifically designed giant magnetoresistance (GMR) probe prior to MFH heat treatment. Experimental results analyzing the distribution of magnetic fluid suggest that different magnetic fluid weight densities could be estimated inside a single tumor by the GMR probe. |
