New method for HA/glucan bone scaffold preparation reduces cytotoxic effect of highly reactive bioceramics
Artykuł w czasopiśmie
MNiSW
35
Lista A
| Status: | |
| Autorzy: | Przekora Agata, Klimek Katarzyna, Wójcik Michał, Pałka Krzysztof, Ginalska Grażyna |
| Dyscypliny: | |
| Aby zobaczyć szczegóły należy się zalogować. | |
| Rok wydania: | 2017 |
| Wersja dokumentu: | Drukowana | Elektroniczna |
| Język: | angielski |
| Wolumen/Tom: | 190 |
| Strony: | 213 - 216 |
| Impact Factor: | 2,687 |
| Web of Science® Times Cited: | 11 |
| Scopus® Cytowania: | 11 |
| Bazy: | Web of Science | Scopus | Web of Science Core Collection |
| Efekt badań statutowych | NIE |
| Materiał konferencyjny: | NIE |
| Publikacja OA: | NIE |
| Abstrakty: | angielski |
| Highly reactive bioceramics deprive culture medium of Ca2+ ions which is lethal to the cells in vitro. The aim of this work was to demonstrate that new method for HA/glucan scaffold fabrication, involving calcium as a cross-linker for β-1,3-glucan gel, may support cell survival in vitro when highly reactive bioceramics are the component of the biomaterial. Two composites made of highly reactive hydroxyapatite (HA) and β-1,3-glucan were prepared basing on 2 different methods. Then, ion reactivity of the materials and cell behaviour on their surfaces were compared. Obtained results proved that new method for HA/β-1,3-glucan fabrication protects against Ca2+ uptake by reactive HA supporting osteoblast growth in vitro. |
